El segundo estudio más galardonado de la ceremonia ha sido Sucker Punch Productions, que gracias a Ghost of Tsushima ha conseguido el premio a mejor arte visual y el reconocimiento de la audiencia. Como mejor juego debut tenemos a Phasmophobia de Kinetic Games, mientras que en móvil el premio ha sido para miHoYo por Genshin Impact. También han sido premiados Dreams (innovación), The Last of Us Parte II (narrativa), Half-Life: Alyx (AR/VR) y Microsoft Flight Simulator (tecnología).
A continuación, la lista completa de ganadores (en negrita) y nominados de los Game Developers Choice Awards 2021.
Mejor audio
- Hades (Supergiant Games)
- The Last of Us Part II (Naughty Dog / Sony Interactive Entertainment)
- Doom Eternal (id Software / Bethesda Softworks)
- Final Fantasy VII: Remake (Square Enix)
- Ghost of Tsushima (Sucker Punch Productions / Sony Interactive Entertainment)
- Phasmophobia (Kinetic Games)
- Umurangi Generation (Origame Digital / Playism, Origame Digital)
- Carrion (Phobia Game Studio / Devolver Digital)
- Mortal Shell (Cold Symmetry / Playstack)
- Raji: An Ancient Epic (Nodding Heads Games / Super!Com)
- Ghost of Tsushima (Sucker Punch Productions / Sony Interactive Entertainment)
- The Last of Us Part II (Naughty Dog / Sony Interactive Entertainment)
- Hades (Supergiant Games)
- Animal Crossing: New Horizons (Nintendo EPD/ Nintendo)
- Half-Life: Alyx (Valve)
- Microsoft Flight Simulator (Asobo Studio / Xbox Game Studios)
- Dreams (Media Molecule / Sony Interactive Entertainment)
- Half-Life: Alyx (Valve)
- Fall Guys: Ultimate Knockout (Mediatonic / Devolver Digital)
- Hades (Supergiant Games)
- The Pathless (Giant Squid / Annapurna Interactive)
- Genshin Impact (miHoYo)
- Legends of Runeterra (Riot Games)
- Alba: A Wildlife Adventure (ustwo / PID Publishing)
- If Found… (Dreamfeel / Annapurna Interactive)
- Kentucky Route Zero: TV Edition (Cardboard Computer / Annapurna Interactive)
- Final Fantasy VII: Remake (Square Enix)
- Hades (Supergiant Games)
- The Last of Us Part II (Naughty Dog / Sony Interactive Entertainment)
- Ghost of Tsushima (Sucker Punch Productions / Sony Interactive Entertainment)
- The Last of Us Part II (Naughty Dog / Sony Interactive Entertainment)
- Half-Life: Alyx (Valve)
- Dreams (Media Molecule / Sony Interactive Entertainment)
- Ghost of Tsushima (Sucker Punch Productions / Sony Interactive Entertainment)
- Microsoft Flight Simulator (Asobo Studio / Xbox Game Studios)
- Ghost of Tsushima (Sucker Punch Productions / Sony Interactive Entertainment)
- Hades (Supergiant Games)
- The Last of Us Part II (Naughty Dog / Sony Interactive Entertainment)
- Ori and the Will of the Wisps (Moon Studios / Xbox Game Studios / iam8bit)
- Cyberpunk 2077 (CD Projekt RED / CD Projekt)
- The Walking Dead: Saints & Sinners (Skydance Interactive)
- Paper Beast (Pixel Reef)
- Dreams (Media Molecule / Sony Interactive Entertainment)
- Half-Life: Alyx (Valve)
- Star Wars: Squadrons (Motive Studios / Electronic Arts)
- Animal Crossing: New Horizons (Nintendo EPD/ Nintendo)
- The Last of Us Part II (Naughty Dog / Sony Interactive Entertainment)
- Half-Life: Alyx (Valve)
- Hades (Supergiant Games)
- Ghost of Tsushima (Sucker Punch Productions / Sony Interactive Entertainment)
- Premio de la audiencia: Ghost of Tsushima
- Pioneer Award: Tom Fulp
- Lifetime Achievement Award: Laralyn McWilliams